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Article

KRAS G12D mutation in Brunner gland adenoma.

BMJ case reports - 27 Jan 2023

Ortega Mahatma, Sparks Jessica, Lichy Jack, Nava Victor E

Abstract excerpt

Brunner gland lesions (BGLs) encompass benign proliferations of the homonymous glands and have been designated as hyperplasia, adenoma (BGA), hamartoma or nodule. In general terms, lesions larger than 0.5 cm are considered true neoplasia with unknown malignant potential and unclear pathogenesis. Genetic alterations have seldom been reported in BGL, and include SMAD4/DPC4 and LRIG1, but not KRAS (Kirsten rat...

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Identifiers

PMID: 36707100
DOI: 10.1136/bcr-2022-252160
PMCID: PMC9884920

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