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Article

Anticholinergic Drug Burden and Risk of Incident MCI and Dementia: A Population-based Study.

Alzheimer disease and associated disorders - 1 Jan 2000

Gildengers Ariel, Stoehr Gary P, Ran Xinhui, Jacobsen Erin, Teverovsky Esther, Chang Chung-Chou H, Ganguli Mary

Abstract excerpt

OBJECTIVE: We investigated whether anticholinergic drug use was related to developing mild cognitive impairment (MCI) or dementia in older adults at the population level. METHODS: We used an Anticholinergic Rating (ACR) scale, Clinical Dementia Rating, APOE genotype, and number of prescription medications. We examined time to incident MCI and incident dementia in a population-based cohort (n=1959). We assessed...

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Identifiers

PMID: 36706325
DOI: 10.1097/WAD.0000000000000538
PMCID: PMC9974875

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