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A complex heterozygous mutation in PADI6 causes early embryo arrest: A case report

10 Jan 2023

Abstract excerpt

Background: The PADI6 gene is a component of the subcortical maternal effect complex (SCMC). Mutations in the PADI6 gene, which was the first gene discovered to impact the activation process of the human embryonic genome, have been shown to induce early embryo arrest. Case: A 29-year-old lady with primary infertility underwent in vitro fertilization embryo transfer (IVF-ET) for tubal reasons, who had normal...

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PMID: 36704355
DOI: 10.3389/fgene.2022.1104085

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