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Article

Novel variants in PADI6 genes cause female infertility due to early embryo arrest.

Journal of assisted reproduction and genetics - 1 Dec 2024

Zhou Juepu, Mao Ruolin, Gao Limin, Wang Meng, Long Rui, Wang Xiangfei, Li Zhou, Jin Lei, Zhu Lixia

Abstract excerpt

PURPOSE: Early embryo arrest is characterized by premature termination of development in preimplantation embryos. Human subcortical maternal complex (SCMC) is a protein complex that is specifically expressed in mammalian oocytes and early embryos and is essential for embryonic cell division. Peptidyl arginine deiminase 6 (PADI6) is proven to be a member of SCMC. Variants in the PADI6 gene have been shown to...

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PMID: 39644447
DOI: 10.1007/s10815-024-03332-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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Novel variants in PADI6 genes cause female infertility due to early embryo arrest.PMID 39644447Read ↗

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A complex heterozygous mutation in PADI6 causes early embryo arrest: A case reportSemantic proximity Read ↗

Mutations in PADI6 Cause Female Infertility Characterized by Early Embryonic Arrest.Semantic proximity Read ↗

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Two novel mutations in PADI6 and TLE6 genes cause female infertility due to arrest in embryonic development.Semantic proximity Read ↗

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