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Article

Pre-pubertal oocytes harbor altered histone modifications and chromatin configuration

10 Jan 2023

Abstract excerpt

Pre-pubertal oocytes are still dormant. They are arrested in a GV state and do not undergo meiotic divisions naturally. A multitude of molecular pathways are changed and triggered upon initiation of puberty. It is not yet clear which epigenetic events occur in oocytes upon pubertal transition, and how significant these epigenetic events may be. We evaluated epigenetic marker levels in mouse pre-pubertal and...

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Identifiers

PMID: 36704200
DOI: 10.3389/fcell.2022.1060440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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