Article
A comprehensive evaluation of rodent malaria parasite genomes and gene expression.
BMC biology - 30 Oct 2014
Otto Thomas D, Böhme Ulrike, Jackson Andrew P, Hunt Martin, Franke-Fayard Blandine, Hoeijmakers Wieteke A M, Religa Agnieszka A, Robertson Lauren, Sanders Mandy, Ogun Solabomi A, Cunningham Deirdre, Erhart Annette, Billker Oliver, Khan Shahid M, Stunnenberg Hendrik G, Langhorne Jean, Holder Anthony A, Waters Andrew P, Newbold Chris I, Pain Arnab, Berriman Matthew, Janse Chris J
Abstract excerpt
BACKGROUND: Rodent malaria parasites (RMP) are used extensively as models of human malaria. Draft RMP genomes have been published for Plasmodium yoelii, P. berghei ANKA (PbA) and P. chabaudi AS (PcAS). Although availability of these genomes made a significant impact on recent malaria research, these genomes were highly fragmented and were annotated with little manual curation. The fragmented nature of the genomes...
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