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Article

CD8+ lymphocytes do not impact SIV reservoir establishment under ART

23 Jan 2023

Abstract excerpt

Abstract Persistence of the human immunodeficiency virus type-1 (HIV-1) latent reservoir in infected individuals remains a problem despite fully suppressive antiretroviral therapy (ART). While reservoir formation begins during acute infection, the mechanisms responsible for its establishment remain unclear. CD8+ T cells are important during the initial control of viral replication. Here we examined the effect of...

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PMID: 36690860
DOI: 10.1038/s41564-022-01311-9

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