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Simulated microgravity reduces quality of ovarian follicles and oocytes by disrupting communications of follicle cells

23 Jan 2023

Abstract excerpt

Ovarian follicles are the fundamental structures that support oocyte development, and communications between oocytes and follicle somatic cells are crucial for oogenesis. However, it is unknown that whether exposure to microgravity influences cellular communications and ovarian follicle development, which might be harmful for female fertility. By 3D culturing of ovarian follicles under simulated microgravity...

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PMID: 36690655
DOI: 10.1038/s41526-023-00248-5

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