Article
Simulated Microgravity Modulates Differentiation Processes of Embryonic Stem Cells
1 Jan 2016
Abstract excerpt
BACKGROUND/AIMS: Embryonic developmental studies under microgravity conditions in space are very limited. To study the effects of altered gravity on the embryonic development processes we established an in vitro methodology allowing differentiation of mouse embryonic stem cells (mESCs) under simulated microgravity within a fast-rotating clinostat (clinorotation) and capture of microarray-based gene signatures....
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