Article
Imaging phenotypes from MRI for the prediction of glioma immune subtypes from RNA sequencing: A multicenter study.
Molecular oncology - 1 Apr 2023
Duan Jingxian, Zhang Zhenyu, Chen Yinsheng, Zhao Yuanshen, Sun Qiuchang, Wang Weiwei, Zheng Hairong, Liang Dong, Cheng Jingliang, Yan Jing, Li Zhi-Cheng
Abstract excerpt
Tumor subtyping based on its immune landscape may guide precision immunotherapy. The aims of this study were to identify immune subtypes of adult diffuse gliomas with RNA sequencing data, and to noninvasively predict this subtype using a biologically interpretable radiomic signature from MRI. A subtype discovery dataset (n = 210) from a public database and two radiogenomic datasets (n = 130 and 55, respectively)...
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