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Article

Radiogenomic profiling of global DNA methylation associated with molecular phenotypes and immune features in glioma.

BMC medicine - 2 Sept 2024

Zhuang Zhuokai, Lin Jinxin, Wan Zixiao, Weng Jingrong, Yuan Ze, Xie Yumo, Liu Zongchao, Xie Peiyi, Mao Siyue, Wang Zongming, Wang Xiaolin, Huang Meijin, Luo Yanxin, Yu Huichuan

Abstract excerpt

BACKGROUND: The radiogenomic analysis has provided valuable imaging biomarkers with biological insights for gliomas. The radiogenomic markers for molecular profile such as DNA methylation remain to be uncovered to assist the molecular diagnosis and tumor treatment. METHODS: We apply the machine learning approaches to identify the magnetic resonance imaging (MRI) features that are associated with molecular...

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Identifiers

PMID: 39218882
DOI: 10.1186/s12916-024-03573-y
PMCID: PMC11367996

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