Article
Molecular Epidemiology of HIV-1 in Ghana: Subtype Distribution, Drug Resistance and Coreceptor Usage.
Viruses - 31 Dec 2022
Appah Anna, Beelen Charlotte J, Kirkby Don, Dong Winnie, Shahid Aniqa, Foley Brian, Mensah Miriam, Ganu Vincent, Puplampu Peter, Amoah Linda E, Nii-Trebi Nicholas I, Brumme Chanson J, Brumme Zabrina L
Abstract excerpt
The greatest HIV-1 genetic diversity is found in West/Central Africa due to the pandemic’s origins in this region, but this diversity remains understudied. We characterized HIV-1 subtype diversity (from both sub-genomic and full-genome viral sequences), drug resistance and coreceptor usage in 103 predominantly (90%) antiretroviral-naive individuals living with HIV-1 in Ghana. Full-genome HIV-1 subtyping confirmed...
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