Article
High resistance to reverse transcriptase inhibitors among persons infected with human immunodeficiency virus type 1 subtype circulating recombinant form 02_AG in Ghana and on antiretroviral therapy.
Medicine - 1 Feb 2020
Deletsu Selase D, Maina Edward K, Quaye Osbourne, Ampofo William K, Awandare Gordon A, Bonney Evelyn Y
Abstract excerpt
This study sought to determine the dominant circulating human immunodeficiency virus type 1 (HIV-1) subtype and associated drug resistance mutations in Ghana.This cross-sectional study was conducted with archived samples collected from patients who received care at 2 hospitals in Ghana from 2014 to 2016. Blood samples were earlier processed into plasma and peripheral blood mononuclear cells and stored at -80 °C....
Topics
- Adult
- Anti-HIV Agents
- Cross-Sectional Studies
- Drug Resistance, Viral
- Evolution, Molecular
- Female
- Ghana
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Male