Article
Associations of vitamin D receptor encoding gene variants with premenopausal breast cancer risk.
American journal of human biology : the official journal of the Human Biology Council - 1 Jun 2023
Iqbal Mehir Un Nisa, Maqbool Syed Amir, Khan Taseer Ahmed
Abstract excerpt
OBJECTIVE: This study evaluates whether vitamin D receptor (VDR) gene variations are associated with premenopausal breast cancer in Pakistani cohorts. METHODS: Genomic DNA was isolated from 228 breast cancer patients and 500 non-cancer controls. Six polymorphic variants (rs11568820, rs4516035, rs2228570, rs1544410, rs7975232, ) of the VDR gene were genotyped using PCR-RFLP analysis. All statistical...
