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Article

Association between the BsmI Polymorphism in the Vitamin D Receptor Gene and Breast Cancer Risk: Results from a Pakistani Case-Control Study.

PloS one - 1 Jan 2015

Rashid Muhammad Usman, Muzaffar Merium, Khan Faiz Ali, Kabisch Maria, Muhammad Noor, Faiz Sabeen, Loya Asif, Hamann Ute

Abstract excerpt

BACKGROUND: Vitamin D is postulated to decrease the risk of breast cancer by inhibiting cell proliferation via the vitamin D receptor (VDR). Two common single nucleotide polymorphisms (SNPs) in the VDR gene, rs1544410 (BsmI) and rs2228570 (FokI), are inconsistently associated with breast cancer risk in Caucasian populations, while data for Asians are scarce. Here, we investigated the possible contribution of...

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Identifiers

PMID: 26517870
DOI: 10.1371/journal.pone.0141562
PMCID: PMC4627649

Genes

BRCA1
VDR

Provenance

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Association between the BsmI Polymorphism in the Vitamin D Receptor Gene and Breast Cancer Risk: Results from a Pakistani Case-Control Study.PMID 26517870Read ↗

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