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Article

ULK1-mediated phosphorylation regulates the conserved role of YKT6 in autophagy

16 Jan 2023

Abstract excerpt

Autophagy is a catabolic process during which cytosolic material is enwrapped in a newly formed double-membrane structure called the autophagosome, and subsequently targeted for degradation in the lytic compartment of the cell. The fusion of autophagosomes with the lytic compartment is a tightly regulated step and involves membrane-bound SNARE proteins. These play a crucial role as they promote lipid mixing and...

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PMID: 36644903
DOI: 10.1242/jcs.260546

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