Article
Systematic identification of gene-altering programmed inversions across the bacterial domain.
Nucleic acids research - 25 Jan 2023
Milman Oren, Yelin Idan, Kishony Roy
Abstract excerpt
Programmed chromosomal inversions allow bacteria to generate intra-population genotypic and functional heterogeneity, a bet-hedging strategy important in changing environments. Some programmed inversions modify coding sequences, producing different alleles in several gene families, most notably in specificity-determining genes such as Type I restriction-modification systems, where systematic searches revealed...
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