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Article

Visual discrimination and inhibitory control deficits in mouse models of Down syndrome: A pilot study using rodent touchscreen technology.

Journal of neuroscience research - 1 Apr 2023

Siegel Ashley Emily, Bianchi Diana W, Guedj Faycal

Abstract excerpt

Several non-verbal cognitive and behavioral tests have been developed to assess learning deficits in humans with Down syndrome (DS). Here we used rodent touchscreen paradigms in adult male mice to investigate visual discrimination (VD) learning and inhibitory control in the Dp(16)1/Yey (C57BL/6J genetic background), Ts65Dn (mixed B6 X C3H genetic background) and Ts1Cje (C57BL/6J genetic background) mouse models...

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Identifiers

PMID: 36602162
DOI: 10.1002/jnr.25160
PMCID: PMC10068543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Visual discrimination and inhibitory control deficits in mouse models of Down syndrome: A pilot study using rodent touchscreen technology.PMID 36602162Read ↗

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