Article
Contrasting co-inheritance of alpha and beta mutations in delta beta thalassemia and hereditary persistence of fetal hemoglobin: a study from India.
Hematology (Amsterdam, Netherlands) - 1 Oct 2018
Pandey Hareram, Ranjan Ravi, Singh Kanwaljeet, Sharma Amit, Kishor Kamal, Seth Tulika, Saxena Renu
Abstract excerpt
BACKGROUND AND OBJECTIVES: Coinheritance of δβ thalassemia and HPFH with inherited factors is sparsely documented and may affect treatment modalities. So, we screened the presence of α deletion and β mutations in δβ thalassemia and HPFH disorders in 52 cases with high Hb F concentration. MATERIAL AND METHODS: Fifty-two individuals with raised HbF levels were study subjects. CZE was done for quantitative...
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