Article
Population structure and genetic diversity of Mycobacterium tuberculosis in Ecuador.
Scientific reports - 10 Apr 2020
Garzon-Chavez Daniel, Garcia-Bereguiain Miguel Angel, Mora-Pinargote Carlos, Granda-Pardo Juan Carlos, Leon-Benitez Margarita, Franco-Sotomayor Greta, Trueba Gabriel, de Waard Jacobus H
Abstract excerpt
Tuberculosis (TB) is a significant public health problem in Ecuador with an incidence of 43 per 100,000 inhabitants and an estimated multidrug-resistant-TB prevalence in all TB cases of 9%. Genotyping of Mycobacterium tuberculosis (MTBC) is important to understand regional transmission dynamics. This study aims to describe the main MTBC lineages and sublineages circulating in the country. A representative sample...
Topics
- Antitubercular Agents
- DNA, Bacterial
- Drug Resistance, Microbial
- Ecuador
- Genetic Variation
- Humans
- Minisatellite Repeats
- Molecular Epidemiology
- Multilocus Sequence Typing
- Mycobacterium tuberculosis