Article
Well-differentiated Sertoli-Leydig Cell Tumors (SLCTs) Are Not Associated With DICER1 Pathogenic Variants and Represent a Different Tumor Type to Moderately and Poorly Differentiated SLCTs.
The American journal of surgical pathology - 1 Apr 2023
McCluggage W Glenn, Rivera Barbara, Chong Anne-Sophie, Clarke Blaise A, Schultz Kris Ann P, Dehner Louis P, Tchrakian Nairi, Apellaniz-Ruiz Maria, Gilks C Blake, Kommoss Friedrich, Stewart Colin J R, Foulkes William D
Abstract excerpt
Sertoli-Leydig cell tumors (SLCTs) are uncommon ovarian sex cord-stromal neoplasms which are currently classified into well, moderately, and poorly differentiated and retiform types. Well-differentiated SLCT is the least common and typically occurs in pure form, whereas moderately and poorly differentiated and retiform types often comprise a morphologic spectrum with an admixture of all 3. DICER1 pathogenic...
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