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Article

Multi-institution analysis of tumor mutational burden and outcomes in pediatric central nervous system tumor patients.

Pediatric blood & cancer - 1 Mar 2023

Parisi Rose, Patel Roshal R, Rood Gavrielle, Bowden Acacia, Turco George, Korones David N, Andolina Jeffrey R, Comito Melanie, Barth Matthew, Weintraub Lauren

Abstract excerpt

BACKGROUND: Pediatric central nervous system (CNS) tumors are the leading cause of pediatric cancer mortality. Research addressing genomic biomarkers and clinical outcomes is needed to inform therapeutic decision-making. METHODS: We conducted a retrospective analysis of pediatric patients (age <21) diagnosed with a primary CNS tumor at four upstate New York hospitals from 2008 to 2021. Clinical and...

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Identifiers

PMID: 36573296
DOI: 10.1002/pbc.30139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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