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Article

Elusive Trans-Acting Factors Which Operate with Type I (Poliovirus-like) IRES Elements

7 Dec 2022

Abstract excerpt

-acting element in the 5' untranslated region (5'UTR) of poliovirus mRNA, which is able to direct initiation at an internal start codon without the involvement of a cap structure, has been called an IRES (Internal Ribosome Entry Site or Segment). Despite its early discovery, poliovirus and other related IRES elements of type I are poorly characterized, and it is not yet clear which host proteins (a.k.a. IRES...

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PMID: 36555135
DOI: 10.3390/ijms232415497

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