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Cross-talk between red blood cells and plasma influences blood flow and omics phenotypes in severe COVID-19

28 Nov 2022

Abstract excerpt

Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and can affect multiple organs, among which is the circulatory system. Inflammation and mortality risk markers were previously detected in COVID-19 plasma and red blood cells (RBCs) metabolic and proteomic profiles. Additionally, biophysical properties, such as deformability, were found to be changed...

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PMID: 36537079
DOI: 10.7554/elife.81316

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