Article
Human beta-defensin 1 circulating level and gene polymorphism in non-segmental vitiligo Egyptian patients.
Anais brasileiros de dermatologia - 1 Jan 2000
Farag Azza Gaber Antar, Shoeib Mohamed Abd AlMoneam, Labeeb Azza Zagloul, Sleem Asmaa Shaaban, Khallaf Hagar Mahmoud AbdElkader, Khalifa Amany Salah, Elshaib Mustafa Elsayed, Elnaidany Nada Farag, Hanout Hayam Mohamed Aboelnasr
Abstract excerpt
BACKGROUND: Vitiligo is an acquired depigmented skin disorder. It has a genetic and autoimmune background. Human beta defensin-1(HBD-1) plus its gene polymorphism were linked to some autoimmune disorders. OBJECTIVE: To elucidate the possible role of HBD-1 in the pathogenesis of non-segmental vitiligo (NSV) through evaluation of HBD-1 serum levels and its single nucleotide polymorphism (SNP) in patients having...
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