Article
Association of human beta-defensin 1 gene polymorphisms with nonsegmental vitiligo.
Clinical and experimental dermatology - 1 Apr 2019
Ochoa-Ramírez L A, Becerra-Loaiza D S, Díaz-Camacho S P, Muñoz-Estrada V F, Ríos-Burgueño E R, Prado-Montes de Oca E, Rangel-Villalobos H, Velarde-Félix J S
Abstract excerpt
BACKGROUND: Vitiligo is a pigmentation disorder of autoimmune aetiology. Polymorphisms in beta-defensin genes have been linked to a predisposition to some autoimmune disorders. AIM: To evaluate the role of polymorphisms in DEFB1, the gene encoding for human beta-defensin (HBD)-1 and its 5' untranslated region in nonsegmental vitiligo. METHODS: In total, 354 participants [171 patients with non-segmental vitiligo...
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