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Article

A novel uveitis model induced by lipopolysaccharide in zebrafish

1 Dec 2022

Abstract excerpt

Objective: Endotoxin-induced uveitis (EIU) is an important tool for human uveitis study. This study was designed to develop a novel EIU model in zebrafish. Methods: An EIU model in zebrafish was induced by intravitreal lipopolysaccharide (LPS) injection and was assessed dynamically. Optical coherence tomography (OCT) was used to assess infiltrating cells in the vitreous body. The histological changes...

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PMID: 36532084
DOI: 10.3389/fimmu.2022.1042849

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