Article
Association of polymorphisms rs2303729, rs10880, and rs1131620 of LTBP4 with sarcopenia in elderly patients with type 2 diabetes mellitus.
Annals of human biology - 1 Dec 2022
Ibarra-Tapia Ingrid Yali, Juárez-Sandoval Ariadna, Pérez Itzel Torres, Cano-Martínez Luis Javier, Sánchez-García Sergio, Ruiz-Batalla Juana Marlen, Aroche-Reyes Irma Angélica, García Silvia, Canto Patricia, Mejía David-Rojano, Coral-Vázquez Ramón Mauricio
Abstract excerpt
BACKGROUND: Latent TGFβ binding protein 4 (LTBP4) modifies skeletal muscle function, and polymorphisms in this gene have been associated with a longer ambulation time in patients with Duchenne muscular dystrophy. However, no studies associate these polymorphisms with an acquired muscle condition. AIM: The study aims to determine whether three functional variants within the LTBP4 were associated with sarcopenia in...
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