Article
Granulocyte concentrate splitting does not affect phenotype and function.
Transfusion - 1 Feb 2023
Koo Sebastian, Offner Robert, Haile Sophie-Marie, Brosig Andreas, Hähnel Viola, Gruber Michael, Burkhardt Ralph, Ahrens Norbert
Abstract excerpt
BACKGROUND: More granulocyte concentrates (GCs) could be produced for more patients from the same donor if apheresis bags were split and stored for longer periods of time. Hence, we tested the hypothesis that splitting and extension of storage of GCs do not impair granulocyte function or viability. STUDY DESIGN AND METHODS: Granulocyte apheresis concentrates were produced using modified fluid gelatin as a...
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