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Osteoarthritis gene therapy in 2022

9 Nov 2022

Abstract excerpt

PURPOSE OF REVIEW: To assess the present status of gene therapy for osteoarthritis (OA). RECENT FINDINGS: An expanding list of cDNAs show therapeutic activity when introduced into the joints of animals with experimental models of OA. In vivo delivery with adenovirus or adeno-associated virus is most commonly used for this purpose. The list of encoded products includes cytokines, cytokine antagonists, enzymes,...

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PMID: 36508307
DOI: 10.1097/bor.0000000000000918

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