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Article

Genome-Wide DNA Methylation Profile Indicates Potential Epigenetic Regulation of Aging in the Rhesus Macaque Thymus.

International journal of molecular sciences - 29 Nov 2022

Qiu Hong, Li Haobo, Fan Ruiwen, Song Yang, Pan Xuan, Zhang Chunhui, Li Jing

Abstract excerpt

We analyzed whole-genome bisulfite sequencing (WGBS) and RNA sequencing data of two young (1 year old) and two adult (9 years old) rhesus macaques (Macaca mulatta) to characterize the genomic DNA methylation profile of the thymus and explore the molecular mechanism of age-related changes in the thymus. Combining the two-omics data, we identified correlations between DNA methylation and gene expression and found...

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Identifiers

PMID: 36499310
DOI: 10.3390/ijms232314984
PMCID: PMC9738698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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