Article
Mendelian randomization suggests a potential causal effect of eosinophil count on influenza vaccination responsiveness.
Journal of medical virology - 1 Jan 2023
Chen Hongwei, Zhang Haoyang, Wen Simin, Xiu Xuehao, You Danming, Zhao Huiying, Wang Dayan, Yang Yuedong, Shu Yuelong
Abstract excerpt
Currently, the clinical factors affecting immune responses to influenza vaccines have not been systematically explored. The mechanism of low responsiveness to influenza vaccination (LRIV) is complicated and not thoroughly elucidated. Thus, we integrate our in-house genome-wide association studies (GWAS) analysis result of LRIV (N = 111, Ncase [Low Responders] = 34, Ncontrol [Responders] = 77) with the GWAS...
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