Article
Investigation of the relationship between MBP gene polymorphisms and delayed encephalopathy after acute carbon monoxide poisoning.
Neurotoxicology - 1 Jan 2023
Zhang Fan, Zeng Jiao, Zhang Xiaoli, Gu Jiapeng, Han Yongkai, Zhang Ping, Li Wenqiang, Gu Renjun
Abstract excerpt
Increasing evidence reveals that delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) results from the combined effects of environmental and genetic factors. The main pathological feature of DEACMP was generalized demyelination of cerebral white matter. Myelin basic protein (MBP) levels in cerebrospinal fluid (CSF) and serum samples from DEACMP patients were elevated. This study investigated the...
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