Article
LRCH1 polymorphisms linked to delayed encephalopathy after acute carbon monoxide poisoning identified by GWAS analysis followed by Sequenom MassARRAY® validation.
BMC medical genetics - 16 Dec 2019
Gu Jiapeng, Zeng Jiao, Wang Xi, Gu Xin, Zhang Xiaoli, Zhang Ping, Zhang Fan, Han Yongkai, Han Yazhou, Zhang Hongxing, Li Wenqiang, Gu Renjun
Abstract excerpt
BACKGROUND: We explored the association of leucine-rich repeats and calponin homology domain containing 1 (LRCH1) gene polymorphisms with genetic susceptibility to delayed encephalopathy after acute carbon monoxide poisoning (DEACMP), which might provide a theoretical basis for the pathogenesis, diagnosis, and prognosis research of DEACMP. METHODS: Four single nucleotide polymorphisms, rs1539177 (G/A), rs17068697...
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