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Article

MMP1 acts as a potential regulator of tumor progression and dedifferentiation in papillary thyroid cancer

21 Nov 2022

Abstract excerpt

Papillary thyroid cancer (PTC) is one of the malignancies with an excellent prognosis. However, in PTC, progression or dedifferentiation into poorly differentiated thyroid cancer (PDTC) or anaplastic thyroid cancer (ATC) extremely jeopardizes patients’ prognosis. MMP1 is a zinc-dependent endopeptidase, and its role in PTC progression and dedifferentiation is unclear. In this study, transcriptome data of PDTC/ATC...

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PMID: 36479070
DOI: 10.3389/fonc.2022.1030590

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