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Article

A novel EDAR variant identified in non-syndromic tooth agenesis: Insights from molecular dynamics.

Archives of oral biology - 1 Feb 2023

Zhao Zhining, Zhang Tingting, Li Tianqi, Ye Yangyang, Feng Chong, Wang Huijuan, Zhang Xiangyu

Abstract excerpt

OBJECTIVE: This study aims to investigate a novel pathogenic variant in a Chinese family of non-syndromic tooth agenesis (NSTA) and study the impact of the variant on related protein and pathway. DESIGN: One NSTA family was collected. Whole exome sequencing and Sanger sequencing were performed on the proband with NSTA and his 5 family members. The pathogenic influence of the mutant is evaluated by bioinformatics...

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Identifiers

PMID: 36470092
DOI: 10.1016/j.archoralbio.2022.105600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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