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CD8+ T Cell Co-Expressed Genes Correlate With Clinical Phenotype and Microenvironments of Urothelial Cancer

19 Nov 2020

Abstract excerpt

Purpose To identify immune-related co-expressed genes that promote CD8+T cell infiltration in bladder cancer, and to explore the interactions among relevant genes in the tumor microenvironment. Method We obtained bladder cancer gene matrix and clinical information data from TCGA, GSE32894 and GSE48075. The “estimate” package was used to calculate tumor purity and immune score. The CIBERSORT algorithm was used to...

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PMID: 33330025
DOI: 10.3389/fonc.2020.553399

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