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Systems biology reveals anatabine to be an NRF2 activator

16 Nov 2022

Abstract excerpt

family (including tobacco and eggplant), has been shown to ameliorate chronic inflammatory conditions in mouse models, such as Alzheimer's disease, Hashimoto's thyroiditis, multiple sclerosis, and intestinal inflammation. However, the mechanisms of action of anatabine remain unclear. To understand the impact of anatabine on cellular systems and identify the molecular pathways that are perturbed, we designed a...

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PMID: 36467029
DOI: 10.3389/fphar.2022.1011184

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