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Article

MCM4 is a novel prognostic biomarker and promotes cancer cell growth in glioma

17 Nov 2022

Abstract excerpt

Background: Gliomas account for 75% of all primary malignant brain tumors in adults and result in high mortality. Accumulated evidence has declared the minichromosome maintenance protein complex (MCM) gene family plays a critical role in modulating the cell cycle and DNA replication stress. However, the biological function and clinic characterization of nine MCM members in low-grade glioma are not yet clarified....

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PMID: 36465369
DOI: 10.3389/fonc.2022.1004324

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