Highlighting the trajectory from intrauterine growth restriction to future obesity

Abstract excerpt

During the last decades several lines of evidence reported the association of an adverse intrauterine environment, leading to intrauterine restriction, with future disease, such as obesity and metabolic syndrome, both leading to increased cardiovascular and cancer risk. The underlying explanation for this association has firstly been expressed by the Barker’s hypothesis, the “ thrifty phenotype hypothesis ”....

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