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Article

Developmental origins of the metabolic syndrome: prediction, plasticity, and programming.

Physiological reviews - 1 Apr 2005

McMillen I Caroline, Robinson Jeffrey S

Abstract excerpt

The "fetal" or "early" origins of adult disease hypothesis was originally put forward by David Barker and colleagues and stated that environmental factors, particularly nutrition, act in early life to program the risks for adverse health outcomes in adult life. This hypothesis has been supported by a worldwide series of epidemiological studies that have provided evidence for the association between the...

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Identifiers

PMID: 15788706
DOI: 10.1152/physrev.00053.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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