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Fetal origins of adult diabetes

1 Sept 2010

Abstract excerpt

According to the fetal origin of adult diseases hypothesis, the intrauterine environment through developmental plasticity may permanently influence long-term health and disease. Therefore, intrauterine growth restriction (IUGR), due either to maternal, placental, or genetic factors, may permanently alter the endocrine-metabolic status of the fetus, driving an insulin resistance state that can promote survival at...

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PMID: 20840260
DOI: 10.1111/j.1749-6632.2010.05683.x

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