Article
BRAFV600E and BRAF-WT Specific Antitumor Immunity in Papillary Thyroid Cancer.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Dec 2022
Ehlers Margret, Schmidt Mathias, Mattes-Gyorgy Katalin, Antke Christina, Enczmann Juergen, Schlensog Martin, Japp Anna, Haase Matthias, Allelein Stephanie, Dringenberg Till, Giesel Frederik, Esposito Irene, Schott Matthias
Abstract excerpt
One feature of papillary thyroid cancer (PTC) is the frequently present somatic BRAFV600E mutation. PTCs are also characterized by a lymphocytic infiltration, which may correlate with an improved clinical outcome. The objective of the study was the characterization of BRAFV600E specific anti-immunity in PTC patients and correlation analyses with the clinical outcome. Fourteen HLA A2 positive PTC patients were...
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