Article
Exploring markers of immunoresponsiveness in papillary thyroid carcinoma and future treatment strategies.
Journal for immunotherapy of cancer - 29 Jul 2024
Mohanty Atish, Afkhami Michelle, Reyes Amanda, Pharaon Rebecca, Yin Holly, Li Haiqing, Do Dana, Bell Diana, Nam Arin, Chang Sue, Gernon Thomas, Kang Robert, Amini Arya, Sampath Sagus, Kulkarni Prakash, Pillai Raju, Villaflor Vicky, Salgia Ravi, Maghami Ellie, Massarelli Erminia
Abstract excerpt
BACKGROUND: The study summarizes the potential use of immunotherapy for BRAF-mutated papillary thyroid cancer (PTC) by analyzing the immune profile of City of Hope PTC patient samples and comparing them to the thyroid dataset available in the TCGA database. MATERIALS AND METHODS: PTC cases with available formalin-fixed paraffin-embedded archived tumor tissue were identified. RNA was extracted from the tumor...
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