Article
Association of Polymorphisms in the Long Non-Coding RNA HOTAIR with Recurrent Pregnancy Loss in a Korean Population.
Genes - 17 Nov 2022
Park Hyeon Woo, Kim Young Ran, Lee Jeong Yong, Ko Eun Ju, Kwon Min Jung, Kim Ji Hyang, Kim Nam Keun
Abstract excerpt
Recurrent pregnancy loss (RPL) affects 1% to 5% of women, with devastating effects on both reproductive health and psychological well-being. Homeobox (HOX) transcript antisense RNA (HOTAIR) is a long non-coding RNA (lncRNA) produced by HOXC; it plays a major role in invasion and development of ovarian and other cancers. The aim of the present study was to analyze effects of HOTAIR polymorphisms (rs4759314 A>G,...
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