Article
Contribution of long noncoding RNA HOTAIR variants to preeclampsia susceptibility in Iranian women.
Hypertension in pregnancy - 1 Feb 2021
Esmkhani Sahra, Sadeghi Hossein, Ghasemian Majid, Pirjani Reihaneh, Amin-Beidokhti Mona, Gholami Milad, Yassaee Fakhrolmolouk, Mirfakhraie Reza
Abstract excerpt
Objective: To investigate the possible association of lncRNA HOTAIR rs920778 and rs874945 polymorphisms with preeclampsia risk in a sample from the Iranian population. Method: The study subjects included 250 preeclamptic women and 250 healthy women. The genotyping for rs920778 and rs874945 polymorphisms were performed using the TP-ARMS-PCR method. Results: HOTAIR rs920778 increased the risk of preeclampsia under...