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The Role of DNA Damage and Repair in Idiopathic Pulmonary Fibrosis

19 Nov 2022

Abstract excerpt

The mortality rate of idiopathic pulmonary fibrosis (IPF) increases yearly due to ineffective treatment. Given that the lung is exposed to the external environment, it is likely that oxidative stress, especially the stimulation of DNA, would be of particular importance in pulmonary fibrosis. DNA damage is known to play an important role in idiopathic pulmonary fibrosis initiation, so DNA repair systems targeting...

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PMID: 36421478
DOI: 10.3390/antiox11112292

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