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Article

Exome-based gene panel analysis in a cohort of acute juvenile ischemic stroke patients:relevance of NOTCH3 and GLA variants.

Journal of neurology - 1 Mar 2023

Härtl Johanna, Hartberger Julia, Wunderlich Silke, Cordts Isabell, Bafligil Cemsel, Sturm Marc, Westphal Dominik, Haack Tobias, Hemmer Bernhard, Ikenberg Benno David, Deschauer Marcus

Abstract excerpt

BACKGROUND: Genetic variants are considered to have a crucial impact on the occurrence of ischemic stroke. In clinical routine, the diagnostic value of next-generation sequencing (NGS) in the medical clarification of acute juvenile stroke has not been investigated so far. MATERIAL AND METHODS: We analyzed an exome-based gene panel of 349 genes in 172 clinically well-characterized patients with magnetic resonance...

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Identifiers

PMID: 36411388
DOI: 10.1007/s00415-022-11401-7
PMCID: PMC9971083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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