Article
Molecular basis of young ischemic stroke.
Current medicinal chemistry - 1 Jan 2013
Bersano Anna, Borellini Linda, Motto Cristina, Lanfranconi Silvia, Pezzini Alessandro, Basilico Paola, Micieli Giuseppe, Padovani Alessandro, Parati Eugenio, Candelise Livia
Abstract excerpt
Epidemiological and family studies have provided evidence on the role of genetic factors in stroke, particularly in stroke occurring at young age. However, despite its impact, young stroke continues to be understudied. This article reviews the existing literature on the most investigated monogenic disorders (CADASIL, Fabry disease, MELAS, RVCL, COL4A1, Marfan and Ehlers-Danlos syndromes) causing stroke in young...
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