Article
SARS-CoV-2 variants of concern surveillance including Omicron using RT-PCR-based genotyping offers comparable performance to whole genome sequencing.
Frontiers in cellular and infection microbiology - 1 Jan 2022
Vanoni Simone, Matulevicius Arnoldas, Avdiu Besard, Scantamburlo Giada, Ulekleiv Camilla, Brzoska Pius M, Furtado Manohar R, Feenstra Jelena D M, Rico Alain, Gandhi Manoj, Giacobazzi Elisabetta, Masi Elisa, Paulmichl Markus, Nofziger Charity
Abstract excerpt
Known SARS-CoV-2 variants of concern (VOCs) can be detected and differentiated using an RT-PCR-based genotyping approach, which offers quicker time to result, lower cost, higher flexibility, and use of the same laboratory instrumentation for detection of SARS-CoV-2 when compared with whole genome sequencing (WGS). In the current study, we demonstrate how we applied a genotyping approach for identification of all...
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